Seroprevalence of Toxoplasma gondii Infection among Pregnant and Aborted Women in Khartoum State, Sudan

Adam Ahmed  Mohamed; Shirehan M. Ibrahim; Nasr M.Nsar  Ahmed; Sahar M.  Seedahmed

doi:10.52981/smlj.v12i1.3129

Adam Ahmed Mohamed Department of Medical Microbiology, Faculty of Medical Laboratories, National University, Khartoum, Sudan
Shirehan M. Ibrahim Department of Medical Microbiology, Faculty of Medical Laboratories, Ibn Sina University, Khartoum, Sudan
Nasr M.Nsar Ahmed Department of Medical Microbiology, Faculty of Medical Laboratories, Omdurman Ahlia University, Khartoum, Sudan
Sahar M. Seedahmed Department of Medical Microbiology, Faculty of Medical Laboratories, international university of Africa, Khartoum, Sudan

DOI: https://doi.org/10.52981/smlj.v12i1.3129

Keywords: Toxoplasma gondii, pregnant women, abortion, Enzyme linked Immune Sorbent assay, IGM, seropositive ,seronegative, seroprevelance.

Abstract

Introduction: Congenital toxoplasmosis occurs in foetuses upon a primo infection of a pregnant woman with T. gondii. According to the trimester of infection, it does only cause miscarriage or stillbirth but also serious and progressive visual, hearing, motor, and cognitive complications in a born child. A crucial step in antenatal care is the detection of T. gondii infection in the pregnant mother and her fetes.

Objective: To determine the sero-prevalence of Toxoplasma gondii infection among pregnant and aborted women and other virile of risk factors studied.

Methods: One hundred pregnant women attending antenatal care in Khartoum State, Sudan collection of 3 ml ,centrifugation, save at 4c can be detected by Enzyme Linked Immunosorbent Assay test for IgM study was conducted from June 2022 to July 2022 screened for immunoglobulin (IgM) antitoxoplasma antibodies using ELISA technique.

Results: Total of 100 pregnant women test were seropositive for IgM was 47 (47%) and while 53 (53%) seronegative. None of the examined women had IgM antitoxoplasma antibodies. The highest rate of infection (25%) was detected among women aged 26-30 years. No statistically significant relation was observed between T.gondii sero-prevalence and other virile of risk factors studied(gestational age, aborted and non-aborted pregnant women, group age, educational level , occupation , demographic data) S (p.value > 0.05).

Conclusions: This study concluded a high seropositivity for Toxopalsma gondii indicating potential for abortion and congenital transmission. Women living in Khartoum higher risks for T. gondii infection. The higher prevalent was in age group (26-30) years. Educational level , occupation , demographic data was statistically significant.

Keywords:

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