Antimicrobial Potential of Acacia nilotica, Subspecies, tomentosa against some Microorganisms that cause Urogenital Infections

Abd-Ulgadir K S1

Abd-Ulgadir K S1

Keywords: Antimicrobial potential; Acacia nilotica subsp. tomentosa; leaves extracts; Bark extract; Antifungal activity

Abstract

Background: For centuries, aromatic plants with therapeutic properties were used to treat human illnesses

Objective: The aim of this study is to investigate and compare the antimicrobial susceptibility of microorganisms that cause urogenital infections to leaves and stem bark extracts of Acacia nilotica spp. Tomentosa, using standard strains and clinical isolates.

Result: The minimum inhibitory concentration (MIC) showed by leaves and bark methanol extracts on the standard bacteria ranged from 3.125 mg/ml to 12.50 mg/ml and the minimum bactericidal concentration (MBC) ranged from 6.25 mg/ml to 50 mg/ml. where the Mean Diameter of Inhibition Zone (MDIZ) ranged from 22.367.40 mm to 25.542.47 mm. On the other hand, isolates of Candida albicans showed MDIZ which was 23.203.44 mm for leaves methanol extract and 25.251.92 mm for bark methanol extract. The MIC exhibited by leaves and bark methanol extracts on bacterial isolates ranged from 3.125 mg/ml to 12.50 mg/ml and the MBC was ranged from6.25 mg/ml to 25 mg/ml.

Conclusion: The study revealed that the extracts of A. n. ssp. tomentosa possess significant antimicrobial compounds, which showed formidable effectiveness against both standard strains and clinical isolates.

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